Jumat, 24 Februari 2012
Kamis, 23 Februari 2012
Scott Phillips and Hyeran Noh note that so-called point-of-care tests include paper strip tests and others performed at home or bedside instead of in laboratories. They show special promise for improving ...
The agonisingly cold dips are a popular way for athletes to finish their training as they help the body to return to normal after a workout.
The theory is that the icy water causes the blood in tired legs to recede. When the legs warm up again they are filled with 'new' oxygenated blood, which invigorates the muscles.
However, scientists at the English Institute ...
Local Anesthesiology Group Becomes First In Arizona To Receive AAAHC Accreditation For Office-Based Anesthesia
New Magnetic Resonance Imaging (MRI) Data Show Efficacy Of SIMPONI® In Treatment Of Rheumatoid Arthritis
In a retrospective study using data from 2005 and 2006, French researchers evaluated the efficacy of second-line chemotherapy in pleural mesothelioma patients who had previously undergone treatment with pemetrexed. The data came from two separate oncology facilities.
The purpose of the study was to determine if multiple rounds of chemotherapy, administered several months apart, could be helpful in slowing the progression of malignant mesothelioma. The use and effectiveness of second-line chemotherapy has not been established for mesothelioma, but patients who are in good physical shape and are still experiencing disease progression may be candidates for the treatment.
Between January 2005 and December 2006, 84 patients with progressing pleural mesothelioma after being treated with pemetrexed were enrolled at the facilities. Of these patients, 44 were treated with second-line chemotherapy. There were 30 men and 14 women. The median age of the patients was 58.
The median time to disease progression after patients received first-line chemotherapy was 6.1 months. Second-line chemotherapy with pemetrexed was then administered in 21 patients while another 20 patients received a new regime (gemcitabine alone or with oxaliplatin). The remaining three patients were enrolled in a Phase I study.
The data showed that four patients experienced a partial response while six patients saw their condition stabilize after receiving second-line chemotherapy treatment. The median time to progression after second-line chemotherapy was 3.8 months. The median survival was 12.2 months.
Four of the initial 44 patients were able to receive third-line chemotherapy and two received fourth-line therapy. Although these results may indicate potential benefits for using second-line chemotherapy on pleural mesothelioma patients, clinical trials are still needed to verify the efficacy of such treatments.
Additional information on mesothelioma may be found through the Mesothelioma Center.
This study presented at the American College of Rheumatology Annual Scientific Meeting in Atlanta also show that this progression may be modified favorably by TNF inhibitors and detrimentally by glucocorticoids.
'These data suggest that by limiting inflammation in RA patients, you can potentially limit ...
The findings of the study will be presented Wednesday, November 10th at the Annual Scientific Meeting of the American College of Rheumatology in Atlanta, Georgia.
The American College of Rheumatology recommends immunofluorescence antinuclear antibody (IF-ANA) testing to help detect the presence ...